Isotopically Labeled Compounds
Medchemexpress LLC Sodium propionate-¹³C | 62601-06-3 | 99.6% | 100 MG
Sodium propionate-13C is the 13C labeled Propionate sodium, an orally active short-chain fatty acid produced by intestinal bacteria from dietary fiber. It is used in research for its various biological activities. Stable heavy isotopes like carbon-13 have been incorporated into drug molecules as tracers for quantitation during drug development, with deuteration also affecting pharmacokinetic and metabolic profiles.
- Increases PPAR-γ
- Inhibits NF-κB activation
- Reduces COX-2 expression and NO production
- Induces apoptosis and autophagy
- Reduces HSV-1-induced keratitis
- Has anticancer effects against glioblastoma
- Exhibits neuroprotective, antioxidant, and anti-inflammatory activities
- Can be used in the research of spinal cord injury and Alzheimer's disease
Medchemexpress LLC Taurocholic acid-d4 (N-Choloyltaurine-d4) | 252030-90-3 | 99.5% | 500 UG
Taurocholic acid-d4 is a deuterium-labeled form of Taurocholic acid, a bile acid involved in the emulsification of fats. This compound is used as a tracer and as an internal standard for quantitative analysis in drug development processes where stable heavy isotopes are incorporated into drug molecules. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes into drug molecules for quantitation.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Veratrole-d2 | 203645-56-1 | 99.7% | 50 MG
Veratrole-d2 is a deuterium-labeled form of Veratrole (1,2-Dimethoxybenzene), a compound naturally found in plants that attracts pollinators. Its release exhibits a circadian rhythm, playing an important role in plant reproduction, species differentiation, and interactions with pollinators. This compound can also be demethylated by cytochrome P-450 in *Streptomyces setonii*. Deuterated compounds like Veratrole-d2 are utilized as tracers for quantification during drug development due to their potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Deuterium-labeled version of Veratrole
- Key compound in plant reproduction and interactions with pollinators
- Can be demethylated by cytochrome P-450
- Used as a tracer for quantification in drug development
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Cayman Chemical Tafluprost-d4 50UG
An internal standard for the quantification of tafluprost by GC- or LC-MS
Medchemexpress LLC 7-keto-Deoxycholic acid | 911-40-0 | 99.7% | 406.56 | 1 ML
7-keto-Deoxycholic acid is a metabolite of bile acids, naturally found in *Clostridium absonum* and convertible by *Lactobacillus* and *Bifidobacterium*. It plays a role in the metabolism of cholic acid and its bioconversion rate increases with the presence of deoxycholic acid. This compound is for research use only.
- Metabolite of bile acids
- Convertible by *Lactobacillus* and *Bifidobacterium*
- Exhibits increased bioconversion rate with deoxycholic acid
- Suitable for research applications
- Solid storage at 4°C, protected from light
- Solution storage at -80°C for 6 months, or -20°C for 1 month, protected from light
Medchemexpress LLC Sofosbuvir-d6 | 1868135-06-1 | 98.07% | 535.49 | 2 MG
Sofosbuvir-d6 is the deuterium-labeled Sofosbuvir, an active inhibitor of HCV RNA replication. It demonstrates potent anti-hepatitis C virus (HCV) activity and is intended for research use only.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated for drug development
- Potential to affect pharmacokinetic and metabolic profiles of drugs
![Revvity Health Sciences Inc UTP, [α-<sup>32</sup>P]- 800Ci/mmol 10mCi/ml EasyTide, 250 µCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502812274.jpg-250.jpg)
Revvity Health Sciences Inc UTP, [α-32P]- 800Ci/mmol 10mCi/ml EasyTide, 250 µCi
UTP, [α-32P]- 800Ci/mmol 10mCi/ml EasyTide, 250 µCi
Cayman Chemical NItenpyram-d3 500ug
An internal standard for the quantification of nitenpyram by GC- or LC-MS
Cayman Chemical DeoxycholIc ACDd4 MaxSpec
A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications
Cayman Chemical EfInaconazole-d4 500ug
An internal standard for the quantification of efinaconazole by GC- or LC-MS
Cayman Chemical PlerIxafor-d4 1mg
An internal standard for the quantification of plerixafor by GC- or LC-MS
Cambridge Isotope Laboratories GLYCAN-O25-13C-GAL4 (GALACTOSE-13C6, 99%), 500 PMOL
GLYCAN-O25-13C-GAL4 (GALACTOSE-13C6, 99%), 500 PMOL
Medchemexpress LLC Meglutol-d3 (dicrotalic acid-d3) | 59060-36-5 | MFCD01074174 | 98.0% | 165.16 | C6H7D3O5 | 10 MG
Meglutol-d3 (dicrotalic acid-d3) is the deuterium-labeled analogue of meglutol, intended for use as a tracer or internal standard in quantitative analysis by NMR, GC-MS, or LC-MS. It is a white to off-white solid with high purity and is supplied in small-mass packages for analytical use.
- Deuterium-labeled internal standard for quantitative analysis
- Purity 98.0%
- Molecular weight 165.16
- Soluble in methanol (100 mg/mL; may require ultrasonic)
- Stored as powder at -20°C (long term) or 4°C (short term)
Sigma Aldrich Fine Chemicals Biosciences 4-Oxo-TEMPO-d16,15N, free radical 98 atom % 15N, 98 atom % D | 80404-14-4 | MFCD00190575 | 100MG
4-Oxo-TEMPO-d16,15N, free radical 98 atom % 15N, 98 atom % D | Purity: 99% (CP) | Mol Wt: 187.32 | 80404-14-4 | MFCD00190575 | 100MG
Cayman Chemical RemdesIvIr-d4 500ug
An internal standard for the quantification of remdesivir by GC- or LC-MS